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Home»News»Gaming News»Toxic Crusaders Mutate San Diego Comic-Con 2025 with New Trailer and Big Surprise

Toxic Crusaders Mutate San Diego Comic-Con 2025 with New Trailer and Big Surprise

By Keith MitchellJuly 23, 2025
Toxic Crusaders Header image 1920x1080

Get ready to mop up some mutant mayhem! With San Diego Comic-Con 2025 just around the corner, indie publisher Retroware is heading West with a radioactive surprise. The team behind the upcoming Toxic Crusaders beat-’em-up will be joining forces with cult film legends Troma for a special celebration—and fans won’t want to miss what’s coming next.

On Saturday, July 26, the worlds of indie gaming and gore-soaked cinema collide during the It’s Troma Time panel, celebrating over 50 years of Troma’s outrageous film legacy. Kicking off at 9:00 pm PDT in Room 25ABC at the San Diego Convention Center, the event promises surprises and shocking reveals.

Troma co-founder and underground icon Lloyd Kaufman will headline the panel with new info on his latest film, Troma’s The Power of Positive Murder. He’ll be joined by:

  • Andrew Miller – Producer
  • Adam Peltier – Star
  • Catherine Corcoran – Actress (Terrifier, Return to Nuke ’Em High)
  • Mathew Klickstein – Author of Lloyd Kaufman Interviews

The panel will be moderated by Megan Silver.

Closing out the panel, Retroware’s Creative Director Justin Silverman will premiere a brand-new gameplay trailer for Toxic Crusaders, an over-the-top beat-’em-up inspired by the 1991 cult cartoon. Following the trailer, Silverman will deliver a major announcement about the game’s release, so if you’re in attendance, you may not want to leave early!

Panel Details

  • Title: It’s Troma Time
  • Date: Saturday, July 26, 2025
  • Time: 9:00 p.m. – 10:00 p.m. PDT
  • Location: Room 25ABC, San Diego Convention Center

Game Features

  • Unleash Co-op Carnage: Relive the arcade glory days with up to four-player local co-op as you mop up Dr. Killemoff’s Radiation Rangers.
  • Mutant Mayhem: Choose from seven playable heroes—Toxie, Nozone, Junkyard, Major Disaster, Headbanger, Yvonne, and Mrs. Junko—each with unique powers.
  • Saturday Morning Slugfest: Dive into an original story that continues the legacy of the 1991 cartoon series.
  • Intoxicating Visuals: Colorful pixel art and expressive animations bring Tromaville’s cartoon chaos to life.

Toxic Crusaders will launch later this year on PlayStation 4, PlayStation 5, Xbox One, Xbox Series X|S, Nintendo Switch, and PC. Wishlist the game now on Steam and check out the demo to get an early taste of the action.

Retroware San Diego Comic-Con 2025 Toxic Crusaders
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Keith has been a fan of geek culture and video games ever since his father gifted him his first gaming console many decades ago and has used this love of for the genres to start The Outerhaven. Keith keeps follows on the ongoings of videogames, anime, comics and technology, and while he has been writing about these topics for the past 14 years, he has been a gamer and tech guy for 30 years.

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